Evening Washington
Friday, February 26, 2021
  • Africa
  • Asia
  • Europe
  • latest news
  • USA News
  • World
  • Other
    • TECH
    • Health
    • Fashion
    • Sports
    • Business
No Result
View All Result
  • Africa
  • Asia
  • Europe
  • latest news
  • USA News
  • World
  • Other
    • TECH
    • Health
    • Fashion
    • Sports
    • Business
No Result
View All Result
Evening Washington
No Result
View All Result
Home Health

Are Some Heartburn Meds Tied to Stomach Cancer?

admin by admin
November 1, 2017
in Health
0
Are Some Heartburn Meds Tied to Stomach Cancer?
0
SHARES
0
VIEWS
Share on FacebookShare on Twitter

RELATED POSTS

Covid-19: White House criticises ‘chaotic’ vaccine rollout

Type 2 diabetes: Mindfulness shown to lower high blood sugar levels – how to practice it

TUESDAY, Oct. 31, 2017 (HealthDay News) — Popping certain heartburn drugs like they're candy might up your odds for stomach cancer, new research suggests.

The risk was proportionate to how long and how often these drugs, called proton pump inhibitors (PPIs), were taken. That risk increased anywhere from two to eight times, the study authors said.

Although the relative risk seems high, the absolute risk was small. But it was statistically significant, especially for people infected with Helicobacter pylori, a bacteria linked to stomach cancer, the researchers explained.

"While PPIs are one of the most commonly used medications for treating reflux disease as well as dyspepsia, clinicians should exercise caution when prescribing long-term PPIs, even to patients who have H. pylori eradicated," said lead researcher Dr. Wai Keung Leung. He is a professor of gastroenterology at the University of Hong Kong.

PPIs include commonly used drugs like Prilosec, Nexium and Prevacid.

Eliminating H. pylori lowers the risk of stomach cancer significantly, Leung noted. But even after the bacteria is treated, many people still develop stomach cancer.

However, this study couldn't prove PPIs cause stomach cancer, only that an association exists. PPIs are generally considered safe.

"The advice to PPI users, particularly those with past H. pylori infection, is to be cautious with the prolonged usage of PPIs," Leung said. "Doctors should review the indications and needs of long-term PPIs in these patients."

The small increase in the risk of stomach cancer with PPIs was not enough to prompt one gastrointestinal specialist to abandon their use.

"In my own experience, I have seen medicine evolve. And one thing that I try to keep in mind is, while many studies exist and treatment is evolving, we must tailor treatment on an individual basis," said Dr. Sherif Andrawes. He is director of endoscopy at Staten Island University Hospital in New York City.

Even with this new study, "there are medical situations in which PPI therapy is necessary and the risk of side effects is lesser than the risk of developing bleeding or cancer of another area in the GI [gastro-intestinal] tract," Andrawes said.

For example, he explained, the medications can help suppress stomach acids and guard against esophageal cancer in those with Barrett's esophagus.

But, "I also try to ensure that if a patient comes in for reflux symptoms, that we try work on lifestyle modification and diet first, rather than initiating PPI therapy," Andrawes added.

Stomach cancer is the third leading cause of cancer death in the world, he noted, and earlier studies have found a link between PPIs and stomach cancer. But the role of H. pylori was less clear.

To try to assess the role the bacteria played, Leung and his colleagues compared the use of PPIs with another class of drugs used to lower stomach acid — histamine H2-receptor antagonists (H2 blockers).

The study followed nearly 63,400 patients treated with a combination of a PPI and two antibiotics to kill H. pylori. The treatment was given over seven days between 2003 and 2012.

The patients were followed for an average of seven years, until the participants either developed stomach cancer, died, or the study ended.

During this time, more than 3,200 people took PPIs for nearly three years, while nearly 22,000 took H2 blockers (Pepcid, Zantac, Tagamet).

In total, 153 people developed stomach cancer after being treated with a PPI and two antibiotics. None of these patients tested positive for H. pylori, but they all had chronic gastritis (inflammation of the stomach lining).

Taking PPIs was linked with more than twice the risk of developing stomach cancer, while taking H2 blockers was not associated with any increased risk, the researchers found.

In addition, people who took PPIs every day had more than four times the risk for stomach cancer, compared with those who used the drug once a week.

And the longer PPIs were used, the greater the risk of developing stomach cancer, the findings showed.

The risk rose five times after more than a year, to more than six times after two or more years, and to more than eight times after three or more years, Leung said.

Recent reports have also linked long-term use of PPIs with pneumonia, heart attack and bone fracture, he added.

The report was published online Oct. 31 in the journal Gut.

More information

Visit the American Cancer Society for more on stomach cancer.

Let's block ads! (Why?)

Original Article

Health

ShareTweetPin
admin

admin

Related Posts

Covid-19: White House criticises ‘chaotic’ vaccine rollout

Covid-19: White House criticises ‘chaotic’ vaccine rollout

by admin
January 24, 2021
0

A senior White House official has criticised the Trump administration's rollout of the Covid-19 vaccine calling it "chaotic" and "very...

Type 2 diabetes: Mindfulness shown to lower high blood sugar levels – how to practice it

Type 2 diabetes: Mindfulness shown to lower high blood sugar levels – how to practice it

by admin
November 24, 2020
0

Type 2 diabetes is characterised by a battle with high blood sugar levels, which can inflict serious damage on the body. High...

Prince George’s Approves Requiring Healthy Kids’ Meals at Restaurants

Prince George’s Approves Requiring Healthy Kids’ Meals at Restaurants

by admin
November 19, 2020
0

A healthy meal and drink will soon be the required default option for kids’ meals at all restaurants in Prince...

Asian Games: Two Indonesian skateboarders secure ticket to final

by webadmin
October 11, 2020
0

When we get out of the glass bottle of our ego and when we escape like the squirrels in the...

Burkina Faso: Growing Violence Threatens Health Care

Burkina Faso: Growing Violence Threatens Health Care

by admin
September 10, 2019
0

Away from the worlds attention, Burkina Faso has been slipping into violence. In less than a year, t..

Next Post
Speed Up the ‘Cancer Moonshot,’ Doctors Urge

Speed Up the 'Cancer Moonshot,' Doctors Urge

Male infertility treatment ‘insensitive’

Male infertility treatment ‘insensitive’

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Sport

Mets retaining Luis Rojas as manager

Mets retaining Luis Rojas as manager

November 24, 2020
Nets no longer focused on James Harden trade pursuit

Nets no longer focused on James Harden trade pursuit

November 24, 2020
  • 21.8M Fans
  • 81 Followers
  • 103k Subscribers
  • 657 Followers
  • 22.9k Followers

MOST VIEWED

  • ‘Amphan’ may bring first flood of year in Assam: CWC

    ‘Amphan’ may bring first flood of year in Assam: CWC

    0 shares
    Share 0 Tweet 0
  • Where to buy Bitcoin in the UK and how does it work

    0 shares
    Share 0 Tweet 0
  • Playboy Model Marisa Papen Arrested For Dragging Cross In Front Of Vatican While Naked

    0 shares
    Share 0 Tweet 0
  • Russia Scores Gold In Women’s Figure Skating, Leaving USA Ladies Without Medals

    0 shares
    Share 0 Tweet 0
  • 24 Of Genie Bouchard’s Sexiest Shots Off The Court [SLIDESHOW]

    0 shares
    Share 0 Tweet 0

CATEGORY

  • Africa
  • Asia
  • Business
  • Europe
  • Fashion
  • Health
  • latest news
  • Sports
  • TECH
  • Uncategorized
  • USA News
  • World

SITE LINKS

  • Log in
  • Entries feed
  • Comments feed
  • WordPress.org
  • Landing Page
  • All Features
  • Get JNews
  • Contact

© 2020 eveningwashington.com.

No Result
View All Result
  • Africa
  • Asia
  • Europe
  • latest news
  • USA News
  • World
  • Other
    • TECH
    • Health
    • Fashion
    • Sports
    • Business

© 2020 eveningwashington.com.